Dr Sheu and colleagues from Taiwan investigated whether dental disease might be associated with a higher recurrence of Helicobacter pylori infection after successful eradication by triple therapy.
The team enrolled consecutive patients with successful H. pylori eradication.
Successful H. pylori eradication was defined by negative results for both histology and 13C-urea breath test performed 6 weeks after triple therapy.
|First-year H. pylori recurrence rate was 13% with dental disease|
Each patient was scheduled for serial urea breath test and dental assessments at the end of the first, second, and third years.
Patients were categorized into a ‘dental disease' group or ‘no dental disease' group at the first-year follow-up.
The researchers transferred patients in the dental disease group whose dental disease had been cured during the second- and third-year follow-up periods to a ‘dental treatment' group.
There were 159 patients with dental disease, and 200 patients without dental disease.
The research team found that the first-year H. pylori recurrence rate was 13% in patients with dental disease, and 4% in patients without dental disease.
At both the second-year and the third-year follow-up, the annual H. pylori recurrence rates were higher in the dental disease group.
Dr Sheu's team concluded, "The presence of dental disease could predispose to recurrent H. pylori infection after successful eradication."
"Dental surveillance and care after H. pylori eradication is a rational step for preventing recurrence of H. pylori, especially in those with dental diseases."