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 20 January 2018

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News

Risk factors for reflux symptoms during pregnancy

The latest issue of the American Journal of Gastroenterology investigates gastroesophageal reflux symptoms during pregnancy.

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Prevalence of gastroesophageal reflux symptoms increases during pregnancy.

There are no longitudinal studies on western populations examining their incidence in each trimester.

Dr Enrique Rey and colleagues from Spain described the natural history of gastroesophageal reflux symptoms in pregnancy.

The research team ascertained whether pregnancy might be associated with a higher risk of developing gastroesophageal reflux symptoms 1 year postpartum.

The research team evaluated 263 pregnant women and age-matched controls.

Incidence of reflux symptoms was 26% in the first trimester
American Journal of Gastroenterology

A telephone survey was conducted, covering pregnant women at 12, 24, and 36 weeks of gestation, and at 1 year postpartum, using a validated questionnaire.

Controls were interviewed at baseline and 21 months later.

The researchers found that the incidence of reflux symptoms was 26% in the first trimester, 24% in the second, and 26% in the third.

Factors associated with developing reflux symptoms in the first trimester were South American origin, and prepregnancy occasional reflux symptoms.

Risk factors of reflux symptoms in the third trimester were cumulative weight gain during pregnancy, and prepregnancy occasional reflux symptoms.

The team observed that incidence of frequent reflux symptoms at 1 year postpartum was higher in pregnant versus control women.

Dr Rey's team commented, "Incidence of gastroesophageal reflux is similar across the 3 trimesters of pregnancy."

"Accumulated weight gain during pregnancy is associated with a higher risk of gastroesophageal reflux symptoms in the third trimester."

"Pregnancy might constitute a risk factor for developing gastroesophageal reflux symptoms 1 year postpartum."

Am J Gastroenterol 2007: 102(11): 2395-2400
29 October 2007

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