The accuracy of conventional colonoscopy to differentiate neoplastic and non-neoplastic polyps is limited, justifying a biopsy for histologic analysis.
Magnifying chromocolonoscopy has emerged as the best tool available for differentiating adenomatous and hyperplastic polyps during colonoscopy.
However, magnifying endoscopes are rarely used in endoscopy units.
|The accuracy of magnifying chromocolonoscopy for differentiating lesions of 5 mm was 94%|
|Journal of Gastroenterology and Hepatology|
Dr Fabian Emura and colleagues from Tokyo further validated the effectiveness of magnifying chromocolonoscopy in the diagnosis of neoplastic colorectal polyps in a screening center.
The team assessed 500 average-risk subjects were randomly divided into 2 groups
The groups consisted of a magnifying chromocolonoscopy group and a conventional chromocolonoscopy group, each of 250 subjects.
Lesions were analyzed according to Kudo's classification of pit pattern, and additionally subdivided into non-neoplastic and neoplastic.
Lesions judged as neoplastic were resected and those judged as non-neoplastic were left in situ.
Resected lesions were analyzed with histopathological examination.
The researchers found that the overall accuracy of magnifying chromocolonoscopy for differentiating neoplastic lesions was higher than that of conventional chromocolonoscopy.
The accuracy of magnifying chromocolonoscopy for differentiating neoplastic lesions of 5 mm was 94%.
The team noted that the accuracy of conventional chromocolonoscopy in differentiating neoplastic lesions of 5 mm was only 78%.
Results were not affected by the macroscopic types.
Dr Emura's team concluded, "Magnifying chromocolonoscopy is superior to conventional chromocolonoscopy for the diagnosis of colorectal neoplastic lesions in the setting of a health testing center."