The researchers conducted a prospective randomized controlled trial to evaluate whether music decreases the dose of sedative medication required for colonoscopy. They also investigated if the combination of music and patient-controlled sedation improves patient acceptance of colonoscopy.
The findings of the study were published in the January 2002 issue of Gastrointestinal Endoscopy.
A total of 165 patients scheduled to undergo elective colonoscopy were randomized to receive one of three different modes of sedation.
These were a combination of music and patient-controlled sedation with a mixture of propofol and alfentanil (Group 1); patient-controlled sedation alone (Group 2); and music alone with diazemuls and meperidine administered intravenously if requested by the patient (Group 3).
Each bolus of patient-controlled sedation delivered 4.8 mg propofol and 12 µg alfentenil.
|Benefits of music with patient-controlled sedation:|
- Lower dose of sedative needed
- Greater satisfaction
- Majority willing to repeat
| Gastrointestinal Endoscopy |
Music was provided by means of a portable compact disc machine with headphones.
Outcome measures assessed immediately after colonoscopy and 24 hours later included dose of patient-controlled sedation used, complications, recovery time, pain score, satisfaction score, and willingness to repeat the procedure with the same mode of sedation.
The mean dose of propofol used in Group 1 was significantly less than Group 2 (0.84 mg/kg vs 1.15 mg/kg).
The researchers found that the mean satisfaction score was higher in Group 1 (7.8), compared with Group 2 (6.8) and Group 3 (7.4).
The majority of patients in Group 1 were willing to repeat the same mode of sedation when queried immediately after colonoscopy (87%) and 24 hours later (75%), which was significantly different from the corresponding results in the other two groups.
Author Danny W.H. Lee, of the North District Hospital, Sheung Shui, Hong Kong, concluded on behalf of the group, "Music can decrease the dose of sedative medication required for colonoscopy.
"The combination of music and patient-controlled sedation was the best-accepted mode of sedation among 3 groups."