Low anterior resection may result in fecal incontinence.
Dr Lange and colleagues identified risk factors for long-term fecal incontinence after total mesorectal excision with or without preoperative radiotherapy.
Between 1996 and 1999, patients with operable rectal cancer were randomized to total mesorectal excision with or without preoperative radiotherapy.
|Fecal incontinence was reported by 62% who had preoperative radiotherapy |
|British Journal of Surgery|
The researchers retrospectively studied 399 eligible patients who underwent low anterior resection at 2 years and 5 years after total mesorectal excision.
At 5 years after surgery fecal incontinence was reported by 62% of patients who had preoperative radiotherapy and 39% of those who did not.
The research team noted that excessive blood loss and height of the tumor were associated with long-term fecal incontinence.
However, this was only observed in patients treated with preoperative radiotherapy.
Dr Lange's team comments, "Fecal incontinence is likely to occur after preoperative radiotherapy and total mesorectal excision, especially when the perineum is irradiated."