Diverticulosis is associated with high intracolonic pressure and a weakened bowel wall.
Chronic colitis is characterized by liquid stools suggestive of low intracolonic pressure and a thickened bowel wall.
Dr Adi Lahat and colleagues from Israel assessed the prevalence of diverticulosis in colitis patients.
The team retrospectively evaluated colonoscopy results of patients with inflammatory bowel disease (IBD)-associated colitis older than 50 years.
The research team compared the results with those of patients who underwent screening colonoscopy.
Only patients with biopsy-proven disease, disease duration of more than 5 years, and disease beyond the distal 20 cm were included.
|Diverticuli occurred in 15% of controls vs 4% with IBD|
|Inflammatory Bowel Diseases|
The researchers identified 1037 patients diagnosed by colonoscopy as suffering from inflammatory bowel disease-associated colitis between 1987 and 2005.
After exclusion of patients who did not meet the inclusion criteria, the study population consisted of 314 inflammatory bowel disease patients.
The team also assessed 1023 age-matched control patients.
The researchers detected diverticuli in 15% of the control group compared with 4% of the inflammatory bowel disease group.
No significant difference in the prevalence of diverticuli was detected between the 3 subtypes of inflammatory bowel disease patients.
The researchers observed that neither disease duration nor the specific colonic segment involved had a significant influence on the prevalence of diverticulosis.
Dr Lahat's team concluded, "Long-standing colonic inflammation in inflammatory bowel disease patients is associated with a lower prevalence of diverticuli."