Dr Ioannis Hazards and colleagues examined the epidemiology and clinical characteristics of small-bowel cancer.
The team retrospectively studied patients with small-bowel tumors between 1980 and 2000.
The research team used data from the Connecticut Tumor Registry.
The team assessed 1060 small-bowel cancer cases, of which 628 were men, and 632 were women.
Mean age at presentation was 65 years.
|The most common location of small-bowel tumors was the ileum|
|Archives of Surgery|
The researchers found the most common location of small-bowel tumors was the ileum, in 30%.
Tumors in the duodenum occurred in 25%, and 15% of patients had tumors in the jejunum.
In 29% of patients, a prior or subsequent tumor of the gastrointestinal tract was reported.
The research team observed that the most prevalent histologic type was carcinoid, followed by adenocarcinoma, and lymphoma.
The team noted that the patient population was predominantly white, followed by African American patients.
The researchers stratified cases consecutive 7-year intervals.
The researchers showed that from 1980 to 1986, there were 11 cases per 100,000 individuals.
From 1987 to 1993, there were 13 cases per 100,000 individuals.
The team found that from 1994 to 2000, there were 15 cases per 100,000 individuals.
Men comprised 45% of cases from 1980 to 1986, 50% of cases from 1987 to 1993, and 53% of cases from 1994 to 2000.
The team noted that African American patients accounted for 8% of all cases from 1980 to 1986, 6% from 1986 to 1993, and 8% of cases from 1994 to 2000.
In 88%, the primary therapy was surgical, including intestinal bypass, radical excision, excisional biopsy, and subtotal or total excision.
Dr Hatzaras' team concluded, “The incidence of small-bowel tumors in Connecticut has increased during the past 2 decades, with the highest rate of increase in men.”
“Carcinoid tumors are the most common small intestinal cancers identified histologically, followed by adenocarcinomas.”
“The former seems to be more frequently seen in the ileum, the latter in the duodenum.”
“Surgery is the treatment of choice for the cure or palliation of small-bowel cancers.”