Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 25 May 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Standard upper endoscopy more effective than capsule endoscopy

Initial endoscopy followed by upper endoscopy appears more effective than esophageal capsule endoscopy in Barrett's screening, shows March's issue of Clinical Gastroenterology & Hepatology.

News image

fiogf49gjkf04

Esophageal capsule endoscopy is a promising new technology for the detection of esophageal pathology.

Potential advantages for Barrett's esophagus screening include ability to return to work as a result of lack of intravenous sedation.

Drs Lauren Gerson and Otto Lin from California assessed lifetime costs and life expectancy for a cohort of 50-year old men with chronic gastroesophageal disease (GERD).

The team designed a Markov model to identify the presence of Barrett's esophagus.

Upper endoscopy was associated with 19 life-years gained
Clinical Gastroenterology & Hepatology

The team compared the base-case strategy of no screening for Barrett's esophagus with 2 competing screening strategies.

The first strategy included esophageal capsule endoscopy followed by upper endoscopy if Barrett's was suspected.

Within this strategy, esophageal capsule endoscopy was followed by upper endoscopy if there was poor visualization.

The second strategy was standard sedated endoscopy followed by upper endoscopy with biopsy.

The researchers obtained cost estimates from a third-party payer perspective.

For each strategy the team determined lifetime costs, life-years gained, and numbers of esophageal cancers detected.

The researchers also determined death rates from esophageal cancer, and procedural deaths.

The research team found that initial endoscopy followed by upper endoscopy was more expensive but more effective compared with the no screening strategy.

Assuming a theoretical cohort of 10,000 patients with GERD, initial endoscopy followed by upper endoscopy cost $1988.

The research team noted that it was associated with 19 life-years gained.

The team found that the cost for esophageal capsule endoscopy was $2392.

The use of esophageal capsule endoscopy was associated with 18 life-years gained.

For the no screening arm, the cost was $901 and was associated with 18 life-years gained.

The incremental cost-effectiveness ratio of screening with endoscopy followed by upper endoscopy compared with no screening was $4530 per life-year gained.

The model was robust to a wide range of sensitivity analyses.

Dr Gerson's team concluded, “Initial endoscopy followed by upper endoscopy appears more effective and less costly vs esophageal capsule endoscopy in patients with chronic GERD undergoing screening for Barrett's esophagus.”

Clin Gastroenterol Hepatol 2007: 5(3): 319-25
27 March 2007

Go to top of page Email this page Email this page to a colleague

 25 May 2018 
Colorectal cancer–specific mortality
 25 May 2018 
Technology to increase colorectal cancer screening
 25 May 2018 
Post‐operative complications in elderly IBD
 24 May 2018 
Patient-reported outcome measures in IBD trials
 24 May 2018 
Alcohol consumption and outcomes in drug-induced liver injury
 24 May 2018 
Precision medicine for tumors
 23 May 2018 
Management of perianal fistulas in Crohn’s disease
 23 May 2018 
Cardiovascular risk in diabetes mellitus with NAFLD
 23 May 2018 
High body mass index is and ulcerative colitis
 22 May 2018 
Worldwide H.pylori prevalence
 22 May 2018 
PPI and risk of stroke
 22 May 2018 
Online tool predicts bowel dysfunction severity prior to anterior resection
 21 May 2018 
Depressive symptoms in IBD youth
 21 May 2018 
PPI use and cognitive decline
 21 May 2018 
Fecal incontinence and quality of life in IBD
 18 May 2018 
Esophageal dilatation in clinical practice 
 17 May 2018 
IBD and later extraintestinal manifestations
 17 May 2018 
Repeat stool DNA testing
 17 May 2018 
IBS and chronic fatigue following GI infection
 16 May 2018 
Factors associated with fecal incontinence
 16 May 2018 
Diagnostic delay in Crohn's disease
 16 May 2018 
Cardiovascular risk in diabetes mellitus with NAFLD
 15 May 2018 
Guidelines for management of Crohn's
 15 May 2018 
Hep B in the Grey Zone
 15 May 2018 
New therapies for CDI
 14 May 2018 
Blood test for the diagnosis of fibrotic NASH
 14 May 2018 
Outcomes at bariatric centers of excellence
 14 May 2018 
Management of perianal fistulas in Crohn’s
 11 May 2018 
Detection of undiagnosed celiac disease
 11 May 2018 
Alcohol consumption and drug-induced liver injury
 10 May 2018 
Colorectal cancer screening
 10 May 2018 
Fibrosis in patients with chronic hepatitis B
 09 May 2018 
Fecal incontinence
 09 May 2018 
Health problems and IBS
 09 May 2018 
Esophageal dilatation in clinical practice 
 07 May 2018 
Omitting antibiotics in uncomplicated acute diverticulitis
 07 May 2018 
Health problems and IBS
 07 May 2018 
Assessment of diminutive colorectal polyps
 04 May 2018 
National Institutes of Health workshop and obesity
 04 May 2018 
Factors associated with fecal incontinence
 04 May 2018 
Colorectal cancer screening and ethnic inequities
 03 May 2018 
Gastrointestinal ultrasound in IBD
 03 May 2018 
Ultransonography in postsurgical recurrence in Crohn's
 02 May 2018 
Symptom assessment in cirrhotic ascites
 02 May 2018 
Hep C antiviral treatment and liver cancer risk
 02 May 2018 
Chronic Hep B
 01 May 2018 
European guidelines on pancreatic cystic neoplasms
 01 May 2018 
Interferon‐free regimens in Hep C
 01 May 2018 
Age at IBD onset and extraintestinal complications
 30 April 2018 
Formula for preterm infants
 30 April 2018 
Primary antibiotic resistance and sequential therapy for H. pylori
 27 April 2018 
Eastern and western practices for endoscopic resection of colorectal lesions
 27 April 2018 
Anxiety scale for chronic esophageal disease
 27 April 2018 
Disease activity in eosinophilic esophagitis
 26 April 2018 
Obesity and physical activity in diverticulosis
 26 April 2018 
Primary sclerosing cholangitis in the USA
 25 April 2018 
Aspirin and pancreatic cancer
 25 April 2018 
Central mediators of irinotecan-induced steatohepatitis
 25 April 2018 
Neuroimaging in Hep C
 24 April 2018 
Scoring system identifies cancer risk in Barrett's

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us