Crohn's disease is a chronic illness that interferes with the daily life of those affected.
Dr Marco Scarpa and colleagues from Italy evaluated long-term health-related quality of life in Crohn's disease patients who have had ileocolonic resection.
The research team assessed 97 Crohn's disease patients, with a mean follow-up of 47 months after ileocolonic resection.
The patients were interviewed by telephone, and responded to the generic cleveland global quality of life questionnaire.
|The Padova quality of life item scores were lower than in controls|
|Inflammatory Bowel Diseases|
The team reported that 63 patients agreed to attend an outpatient clinic to have a Crohn's Disease Activity Index assessment, and a blood test.
The patients answered the disease-specific Padova Inflammatory Bowel Diseases Quality of Life questionnaire.
The researchers also enrolled control groups.
The researchers found that the Cleveland global quality of life scores of the 97 Crohn's disease patients were similar to those of 69 healthy controls.
The team observed that only the item on current quality of health was scored significantly lower by patients with Crohn's disease.
In contrast, the team noted that the Padova Inflammatory Bowel Diseases Quality of Life item scores were lower than those of the respective healthy controls.
The researchers found that total scores of the Crohn's disease patients were all significantly lower than controls.
On further analysis, the team showed that the Cleveland global quality of life score had a linear relationship with daily stools, and with Crohn's activity index scores.
In addition, the researchers observed a linear relationship between the Padova inflammatory bowel diseases quality of life score and Crohn's activity index scores.
Dr Scarpa's team concluded, “Crohn's disease patients who have undergone ileocolonic resection have an apparently normal quality of life with a good energy level.”
“However, as shown by the Cleveland global quality of life, their long-term health-related quality of life is still affected by a significantly impaired quality of health.”
“In fact, the Padova inflammatory bowel diseases quality of life questionnaire showed significant impairment of bowel and systemic symptom domains with important consequences for emotional and social functions.”
“Health-related quality of life seems to be significantly related only to current disease activity.”