Some studies suggest a positive association between increasing body mass index and risk for colorectal neoplasia.
The impact on screening has not been examined.
Dr Joseph Anderson and colleagues performed a cross-sectional study to examine the association of body mass index, and colorectal neoplasia in a screening population.
|The association was strongest with a body mass index of 40 or more|
|Journal of Clinical Gastroenterology|
The investigative team assessed data collected for 2493 patients presenting for screening colonoscopy.
The data included known risk factors for colorectal neoplasia, demographic information, and lifestyle factors.
The team's outcome was the endoscopic detection of significant colorectal neoplasia that included adenocarcinoma, and high-grade dysphasia.
Endoscopic detection also included villous tissue, adenomas 1 cm or greater, and multiple adenomas of any size.
The investigative team observed an increased risk and prevalence for significant colorectal neoplasia in women as body mass index increased.
The team noted that this relationship was the strongest for the women with a body mass index of 40 or more.
The investigators observed no such relationship in the male population.
Dr Anderson‘s team concluded, “Increasing body mass index, in our population, was associated with an increase risk for colorectal neoplasia in female patients.”
“This study reinforces the importance of screening colonoscopy especially in obese women.”