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 21 June 2018

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IgG1-mediated pro-inflammatory autoreactivity against annexin A11 in patients with IgG4-RD may be attenuated by formation of annexin A11-specific IgG4 antibodies supporting an anti-inflammatory role of IgG4 in IgG4-RD 20 April 2018
Two annexin A11 epitopes targeted by IgG1 and IgG4 autoantibodies were shared between patients with IAC/AIP and IgG4 antibodies blocked binding of IgG1 antibodies to the shared annexin A11 epitopes January's issue of Gut explores Annexin A11 is targeted by IgG4 and IgG1 autoantibodies in IgG4-related disease
Full story
Adalimumab with azathioprine in moderate to severe Crohn's disease 20 April 2018
Adalimumab with azathioprine in Crohn's The most recent publication of the Clinical Gastroenterology & Hepatology examines clinical and pharmacokinetic factors associated with adalimumab-induced mucosal healing in patients with Crohn’s disease.
Full story
c-Myc overexpression can contribute to pancreatic cancer 19 April 2018
c-Myc expression and pancreatic cancer April's issue of Gut investigates c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis.
Full story
Regional variations in olmesartan prescription in the USA 19 April 2018
Olmesartan prescription in the USA This month's issue of Clinical Gastroenterology and Hepatology explores regional patterns of olmesartan prescription and the prevalence of duodenal villous atrophy throughout the United States.
Full story
Chronic hepatitis C treatments that increase patient-reported outcomes scores 18 April 2018
Hep C treatment for sustained virologic response This month's issue of Clinical Gastroenterology and Hepatology investigates patient-reported outcomes following treatment of chronic hepatitis C virus infection with sofosbuvir and velpatasvir, with or without voxilaprevir.
Full story
Minimally invasive surgical and endoscopic necrosectomy reduces death rates 18 April 2018
Endoscopic necrosectomy reduces risk of death <br abp=" /> The most recent publication of Gut considers minimally invasive and endoscopic versus open necrosectomy for necrotising pancreatitis.
Full story
Training program reduces ERCP-associated patient radiation exposure 17 April 2018
Training programs should consider radiation education for advanced endoscopy fellows<br>

This month's publication of Clinic Gastroenterology and Hepatology examines effects of a brief educational program on optimization of fluoroscopy to minimize radiation exposure during endoscopic retrograde cholangiopancreatography.

Full story
Surgery for non-malignant colorectal polyps has increased 16 April 2018
Surgery for colorectal polyps has increased  The most recent publication of Gastroenterology examines the increasing rates of surgery for patients with non-malignant colorectal polyps in the United States.
Full story
Enhanced tests identify advanced liver fibrosis in alcoholic patients with high diagnostic accuracy 16 April 2018
Advanced fibrosis can be ruled out in primary health care patients<br abp=" /> April's issue of Gastroenterology investigates accuracy of the enhanced liver fibrosis test vs fibroTest, elastography, and indirect markers in detection of advanced fibrosis in patients With alcoholic liver disease.
Full story
Long-term antibiotic use in early adulthood associated with increased risk of colorectal adenoma
16 April 2018
Antibiotic use and colorectal adenoma<br abp=" /> This month's issue of Gut considers long-term use of antibiotics and risk of colorectal adenoma.
Full story
MED12 as a tumor suppressor in colorectal cancer 13 April 2018
Colorectal cancer cell lines April's issue of Gut considers MED12 which is recurrently mutated in Middle Eastern colorectal cancer.
Full story
Increasing dose of infliximab does not lead to corticosteroid-free clinical remission in Crohn's 13 April 2018
Infliximab and corticosteroid-free clinical remission in Crohn's The most recent issue of Gastroenterology finds that increasing infliximab dose based on symptoms, biomarkers, and serum drug concentrations does not increase clinical, endoscopic, and corticosteroid-free remission in patients with active luminal Crohn’s disease.
Full story
Children in Scotland will be the first in the UK to benefit from teduglutide
13 April 2018
Teduglutide for children with short bowel syndrome The Scottish Medicines Consortium (SMC), has published advice accepting a new medicine for use by NHS Scotland for treatment of short bowel syndrome in children.
Full story
Heavy use of strong opiates among patients with IBD associates with increased all-cause premature mortality 12 April 2018
Prescriptions for opiate drugs amongst primary care patients with IBD This month's issue of Clinical Gastroenterology and Hepatology explores increasing prescription of opiates and mortality in patients With inflammatory bowel diseases.
Full story
non–Clostridium difficile bacterial infections are rare in patients with flares of IBD
12 April 2018
non–<em>Clostridium difficile</em> bacterial infections in IBD This month's publication of Clinical Gastroenterology and Hepatology finds that non–Clostridium difficile bacterial infections are rare in patients with flares of
inflammatory bowel disease.
Full story

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