Ménétrier’s disease.There is great variation in the thickness and configuration of normal gastric rugae. Endoscopists and radiologists therefore tend to overdiagnose Ménétrier's disease .
In this rare disorder there is marked thickening , tortuosity and irregularity of the mucosal ridges, occasionally giving the mucosa an appearance suggestive of polyposis (Fig. 2.456). Accurate diagnosis must be based on a combination of endoscopic and histopathological appearances (Fig. 2.457).
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