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 21 March 2018

Advanced search - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder


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Colonic diaphragm disease.
This 72-year-old woman on long-term slow-release diclofenac (SR-D) for non-specific arthritis presented with 10 kg weight loss, diarrhea and normocytic anemia (Hb-9g/dl) with an ESR of 103, leucocyte count of 18.3, CRP of 91mg/l, platelet-count of 600 and positive FOBs. Oesophagogastroduodenoscopy (OGD) was non-diagnostic. Colonoscopy revealed benign discrete ulcers and a diaphragmatic stricture in the colon. Withdrawal of NSAID led to dramatic clinical improvement, with 12 kg weight gain, disappearance of arthritic pain, resolution of anemia, and normalization of inflammatory markers.


Pradip Singh, Stafford, UK

Colonic diaphragm disease.

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