Crohn's disease of the colon and appendix.This DCBE of a 17-year-old girl with several months' history of diarrhoea, weight loss and iron-deficiency anaemia shows complete loss of the haustral pattern, generalized reduced distensibility and a very widespread cobblestone pattern, resulting from mucosal edema interspersed by longitudinal and transverse ulcers. The appendix is similarly affected. The terminal ileum is conspicuously normal.
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