Pathology of colorectal polyps(a) Malignant polyp with invasive grade 2 adenocarcinoma invading the upper stalk. The invasive front (arrow) is located 5 mm from the cauterized margin, well above the 1-mm margin recommended for considering conservative management. (b) Higher magnification showing the point of deepest cancer invasion. The malignant glands are angulated and surrounded by cellular fibrous stroma (desmoplastic reaction). (c) Malignant polyp containing extensive invasive grade 3 adenocarcinoma with a margin of less than 1 mm from the transection line (arrow). The high grade of the cancer and the inadequate margin would each weigh independently against conservative management.
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This image is taken from Reproduced, with permission, from Colonoscopy (ed. J. D. Waye, D. K. Rex, and C. B. Williams), Blackwell Publishing (2003).
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