Omeprazole treatment of children with peptic esophagitis refractory to ranitidine therapy
Karjoo M., Kane R. Arch. Pediatr Adolesc Med. 1995; 149: 267-71
Over 150 children prospectively underwent upper endoscopy for complaints of epigastric pain revealing oesophagitis in 84%. They were then treated with ranitidine. Seventy per cent responded to the ranitidine with the remainder progressing onto omeprazole, when 87% responded. The conclusion is that oesophagitis is fairly common in children, especially when there are specific symptoms, and usually is very responsive to therapy.
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